Glow Skin 112mg

What GHK-Cu, BPC-157 and TB-500 Are

GHK-Cu is a copper-binding tripeptide (glycyl-L-histidyl-L-lysine complexed with a copper ion), naturally occurring in human plasma at low concentration and studied for its role in fibroblast signalling and extracellular-matrix remodelling. It carries CAS number 89030-95-5, molecular formula C14H22CuN6O4, and a molecular weight of approximately 401.9 g/mol.

BPC-157 is a synthetic 15-amino-acid peptide derived from a partial sequence identified in human gastric juice protein, studied in preclinical models for its effects on tissue-repair signalling pathways. It carries CAS number 137525-51-0, molecular formula C62H98N16O22, and a molecular weight of approximately 1,419.5 g/mol.

TB-500 is the synthetic, N-acetylated 7-amino-acid fragment (Ac-LKKTETQ) corresponding to residues 17–23 of thymosin beta-4 (Tβ4), a naturally occurring 43-amino-acid protein — commercially sold "TB-500" is this short fragment, not the full protein, a distinction some listings blur. It carries CAS number 885340-08-9, molecular formula C38H68N10O14, and a molecular weight of approximately 889.0 g/mol.

These three peptides act through different mechanisms — copper-dependent fibroblast and collagen signalling for GHK-Cu, and separate tissue-repair pathways under investigation for BPC-157 and TB-500 — which is why they are combined in dermatological and regenerative research contexts rather than being interchangeable with one another.

What Current Research Says

A 2025 peer-reviewed review (Adnan et al., International Journal of Medical Sciences) examined tripeptides in wound healing and skin regeneration and identified GHK-Cu as the most extensively studied of the group, reporting that it "promotes fibroblast proliferation, collagen synthesis, angiogenesis, and ECM remodeling" through copper-dependent mechanisms, and that it reduces inflammatory cytokine signalling (TNF-α, IL-6) in cell-based models. This built on earlier foundational work by Maquart et al. (1988, FEBS Letters), which first reported that the complex stimulated collagen synthesis in cultured skin fibroblasts at picomolar-to-nanomolar concentrations, and a broader 2018 review by Pickart and Margolina (International Journal of Molecular Sciences) covering GHK-Cu's regenerative signalling and gene-expression effects.

BPC-157 and TB-500 have their own separate preclinical research bases. A 2025 systematic review (Vasireddi et al., HSS Journal) examined BPC-157's investigated role in tissue-repair signalling pathways, and a 2026 scoping review (McGuire et al., Applied Sciences) covered current preclinical evidence for both BPC-157 and TB-500 across tissue-repair models.

None of these findings constitute a treatment, cosmetic-efficacy, or health claim for this research-use product; they describe laboratory and preclinical findings for each peptide studied individually, not what a research-use blend sold by Synedica UK does when applied to skin or tissue.

Specifications

Purity, Batch Testing and Certificate of Analysis Standards

Every Glow Skin 112mg pen kit offered for sale is supplied with third-party analytical documentation rather than a single purity percentage repeated across listings. A Certificate of Analysis (COA) for a multi-component blend like this one should confirm the individual milligram amount of each peptide (GHK-Cu, BPC-157, and TB-500), not only the combined 112mg total, along with the analytical method used (typically HPLC or mass spectrometry), the batch or lot number, and the issuing laboratory. "Glow"-style blends are sold at differing component ratios across the market, so researchers should treat a listing that gives only a total milligram figure — with no per-peptide breakdown available on request — as a red flag rather than an oversight. See our contact page to request a Certificate of Analysis for a specific batch.

Sourcing and Verification

Buying a three-component blend like this from a UK-based supplier does not remove the need to verify what arrives. Before ordering, check that the listing states research-use status clearly, that batch documentation is offered rather than promised only "on request," and that each compound's identity (CAS number, molecular formula) is independently verifiable against a source such as PubChem. Because "TB-500" specifically refers to a synthetic 7-amino-acid fragment rather than the full thymosin beta-4 protein, confirming that a supplier's documentation reflects this correctly is a useful additional check. Glow Skin 112mg is offered for sale on this basis, with documentation available per batch. Researchers examining the individual repair-pathway peptides may also find the Synedica BPC-157 & TB-500 Blend relevant, and the full catalogue is browsable on the research products page.